In spring 2018, Abiomed announced the launch of the Women’s Initiative for Heart Recovery focused on heart recovery education and awareness. This builds off our expanded label indication for the Impella heart pump to include patients with Peripartum Cardiomyopathy (PPCM) with cardiogenic shock. 

This efforts aims to assist the underserved female population receive the cardiovascular care they need.

Women's Initiative Press Release

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Cardiomyopathy Fact Sheet

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Cardiovascular Disease

is the number one killer of women and causes 35% of deaths in American women over the age of 20.

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Peripartum Cardiomyopathy

occurs during pregnancy or after childbirth and is a leading cause of pregnancy-related deaths in the United States.

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is the number one cause of heart attacks in young women6 and the average age is 42.

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According to the Centers for Disease Control and Prevention (CDC), cardiovascular disease is the number one killer of women and causes 35% of deaths (approximately 430,000) in American women over the age of 201. Two causes of death as a result of cardiogenic shock, specific to the female population are PPCM and spontaneous coronary artery dissection (SCAD).

PPCM occurs during pregnancy or after childbirth and is a leading cause of pregnancy-related deaths in the U.S2. The disease is often difficult to diagnose, with a mortality rate of 10%, mainly driven by cardiogenic shock. This condition can lead to poor outcomes for the infant and carries a high risk of relapse in subsequent pregnancies3,4,5. With Impella support, patients can have minimally invasive therapy and avoid invasive surgeries and severe drug therapy.

SCAD is a spontaneous tear in the coronary artery that may lead to cardiogenic shock or sudden death. SCAD is the number one cause of heart attacks in young women6and the average age is 427. SCAD often occurs in patients who are active and healthy and 90 percent are women.

Impella® heart pumps offer the unique ability to stabilize the patient's hemodynamics and unload the heart, which allows the muscle to rest and potentially recover its native function. Heart recovery is the ideal option for a patient's quality of life and as documented in several clinical papers, has the ability to save costs for the healthcare system8,9,10.

  1. Heart Disease Statistics. CardioSmart, American College of Cardiology:
  2. Centers for Disease Control and Prevention, Trends in Pregnancy-Related Deaths:
  3. Kolte D, Khera S, et al. Temporal Trends in Incidence and Outcomes of Peripartum Cardiomyopathy in the United States: A Nationwide Population-Based Study. J Am Heart Assoc. 2014 Jun 4;3(3):e001056. doi: 10.1161/JAHA.114.001056.
  4. Bhattacharyya, A., Sukhdeep, SB, et al. Peripartum Cardiomyopathy: A Review.Tex Heart Inst J. 2012; 39(1): 8—16.
  5. Sliwa K, Hilfiker-Kleiner D, et al. Current State of Knowledge on Aetiology, Diagnosis, Management, and Therapy of Peripartum Cardiomyopathy: A Position Statement from the Heart Failure Association of the European Society of Cardiology Working Group on Peripartum Cardiomyopathy. Eur J Heart Fail. 2010;12(8): 767—78.
  6. Grosseto D, Santarelli A, Carigi S, Baldazzi F, Franco N, Santoro D et al. Incidence of Spontaneous Coronary Artery Dissection in All Comers Patients Referred for Acute Coronary Syndrome [abstract 194] Eur Heart J: Acute Cardiovasc Care. 2012;1(1 Suppl):61.
  7. Hayes SN. Spontaneous Coronary Artery Dissection (SCAD): New Insights into This Not-So-Rare Condition. Texas Heart Institute Journal. 2014;41(3):295-298. doi:10.14503/THIJ-14-4089.
  8. Maini B, Gregory D, Scotti DJ, Buyantseva L. Percutaneous Cardiac Assist Devices Compared with Surgical Hemodynamic Support Alternatives: Cost-Effectiveness in the Emergent Setting. Catheter Cardiovasc Interv. 2014 May 1;83(6):E183-92.
  9. Cheung A, Danter M, Gregory D. TCT-385 Comparative Economic Outcomes in Cardiogenic Shock Patients Managed with the Minimally Invasive Impella or Extracorporeal Life Support. J Am Coll Cardiol. 2012;60(17_S).
  10. Gregory D, Scotti DJ, de Lissovoy G, Palacios I, Dixon, Maini B, O'Neill W. A value-based Analysis of Hemodynamic Support Strategies for High-Risk Heart Failure Patients Undergoing a Percutaneous Coronary Intervention. Am Health Drug Benefits. 2013 Mar;6(2):88-99