Publications

Importance of Cardiac Power Output (CPO)

LV Mechanics: Unloading, Pressure-Volume Area (PVA)

Hemodynamics of Impella

Weber DM, Raess DH, et al. Principles of Impella Cardiac Support: The New Science of Cardiac Support in the Cath Lab. Cardiac Interventions Today 2009;SUPP:1-20

Meyns B, Stolinski J, Leunens V, et al. Left Ventricular Support By Catheter-Mounted Axial Flow Pump Reduces Infarct Size. J Am Coll Cardiol 2003;41(7):1087-95

Remmelink M, Sjauw KD, Henriques JP, et al. Effects Of Left Ventricular Unloading By Impella Recover LP2.5 On Coronary Hemodynamics. Catheter. Cardiovasc Interv 2007:70(4):532-37

Aqel RA, Hage FG, Iskandrian AE. Improvement Of Myocardial Perfusion With A Percutaneously Inserted Left Ventricular Assist Device. J Nucl Cardiol 2009doi:10.1007/s12350-009-9127-4

Lam K, Sjauw KD, Henriques JP, de Mol BA. Improved Microcirculation In Patients With An Acute ST-Elevation Myocardial Infarction Treated With The Impella LP2.5 Percutaneous Left Ventricular Assist Device. Clin Res Cardiol 2009; DOI 10.1007/s00392-009-0006-4

Reesink KD, Dekker AL, Van Ommen V, et al. Miniature Intra-cardiac Assist Device Provides More Effective Cardiac Unloading And Circulatory Support During Severe Left Heart Failure Than Intra-aortic Balloon Pumping. Chest 2004;126(3):896-902

Valgimigli M, Steendijk P, Sianos G, et al. Left Ventricular Unloading And Concomitant Total Cardiac Output Increase By The Use Of Percutaneous Impella Recover LP 2.5 Assist Device During High-Risk Coronary Intervention. Catheter Cardiovasc Interv 2005;65(2):263-67

Remmelink M. Sjauw KD, Henriques JP, et al. Effects Of Mechanical Left Ventricular Unloading By Impella On Left Ventricular Dynamics In High-Risk And Primary Percutaneous Coronary Intervention Patients. Catheter Cardiovasc Interv 2010;75(2)187-94

Naidu S. Novel Percutaneous Cardiac Assist Devices. The Science of and Indications for Hemodynamic Support. Circulation.2011; 123: 533-543

Sauren LDC, Accord RE, Hamzeh K, et al. Combined Impella And Intra-Aortic Balloon Pump Support To Improve Both Ventricular Unloading And Coronary Blood Flow For Myocardial Recovery: An Experimental Study. Artif Organs 2007;31(11):839-42

Impella Clinical Studies

Dixon SR, Henriques JP, Mauri L, et al. A Prospective Feasibility Trial Investigating The Use Of The Impella 2.5 System In Patients Undergoing High-Risk Percutaneous Coronary Intervention (The PROTECT I Trial). J Am Coll Cardiol Intv 2009;2:91-96

Engstrom AE, Piek JJ, Henriques JP. Percutaneous Left Ventricular Assist Devices For High-Risk Percutaneous Coronary Intervention. Expert Reviews 2010:1247-55

Sjauw KD, Konorza T, Erbel R, et al. Supported High-Risk Percutaneous Coronary Intervention With The Impella 2.5 Device, The Europella Registry. J Am Coll Cardiol 2009;54(25):2430-34

Kovacic JC, Nguyen H, Karajgikar R, et al. The Impella Recover 2.5 And TandemHeart Ventricular Assist Devices Are Safe And Associated With Equivalent Clinical Outcomes In Patients Undergoing High-Risk Percutaneous Coronary Intervention. Online Manuscript 2011

Burzotta F, Paloscia L, Trani C, et al. Feasibility And Long-Term Safety Of Elective Impella-Assisted High-Risk Percutaneous Coronary Intervention: A Pilot Two-Centre Study. J Cardiovasc Med. 2008 oct;9(10):1004-10

Ferreiro JL, Gomez-Hospital JA, Cequier AR, et al. Use Of Impella Recover LP 2.5 In Elective High Risk Percutaneous Coronary Intervention Int J Cardiol 2009; doi:10.1016/j.ijcard.2009.08.003

Seyfarth M, Sibbing D, Bauer I, et al. A Randomized Clinical Trial To Evaluate The Safety And Efficacy Of A Percutaneous Left Ventricular Assist Device Versus Intra-Aortic Balloon Pumping For Treatment Of Cardiogenic Shock Caused By Myocardial Infarction. J Am Coll Cardiol 2008;52(19):1584-88

Sjauw KD, Remmelink M, Baan J, et al. Preliminary Experience Of The MACH 2 Trial: Safety And Feasibility Of The Left Ventricular Support With The Impella 2.5 Device In Patients With Acute ST-Segment Elevations Myocardial Infarction. J Am Coll Cardiol 2007;914-211:29B

Engström A, Sjauw K, Baan J, et al. Long-term safety and sustained left ventricular recovery: long-term results of percutaneous left ventricular support with Impella LP2.5 in ST-elevation myocardial infarction. EuroIntervention. 2011 Feb;6(7):860-5

Inotropic Support

Intra-Aortic Balloon (IAB)

Other Percutaneous Cardiac Support Devices

Heart Recovery

Anderson M, Smedira N, Samuels L, et al. Use Of The AB5000 Ventricular Assist Device In Cardiogenic Shock After Acute Myocardial Infarction. Ann Thorac Surg 2010;90(3):706-712

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Quick Facts

Impella 2.5/5.0: Minimally invasive, percutaneous heart pump catheters with flows up to 2.5/5.0 liters/minute respectively
More than 100 Publications & Cases in journals/abstracts available on the Impella devices
Over 5,000 patients supported by the Impella Family of products in the United States
The Impella has 56 worldwide patents
Impella is "changing how everybody is practicing."

“It’s making this product available for everybody so that they can increase the complexity of the cases they do.  With the Abiomed support team available, it’s changing how everybody is practicing.”

Richard Shlofmitz – St. Francis Hospital, Roslyn, NY