Importance of Cardiac Power Output (CPO)
Fincke R, Hochman JS, Lowe AM, et al. Cardiac Power Is The Strongest Hemodynamic Correlate of Mortality in Cardiogenic Shock: A Report From the SHOCK Trial Registry. J Am Coll Cardiol 2004;44(2):340-8
den Uil CA, Lagrand WK, van der Ent M, et al. Impaired Microcirculation Predicts Poor Outcome Of Patients With Acute Myocardial Infarction Complicated By Cardiogenic Shock. Eur Heart J 2010;31(24):3032-39
Mendoza DD, Cooper HA, Panza JA. Cardiac Power Output Predicts Mortality Across A Broad Spectrum Of Patients With Acute Cardiac Disease. Am Heart J 2007;153:366-70
Torgersen C, Schmittinger CA, Wagner S, et al. Hemodynamic Variables And Mortality In Cardiogenic Shock: A Retrospective Cohort Study. Crit Care 2009;13:R157
Torre-Amione G, Milo-Cotter O, Kaluski E, et al. Early Worsening Heart Failure In Patients Admitted For Acute Heart Failure: Time Course, Hemodynamic Predictors, And Outcome. J Card Fail 2009;15(8):639-44
LV Mechanics: Unloading, Pressure-Volume Area (PVA)
Suga H. Total Mechanical Energy Of A Ventricle Model And Cardiac Oxygen Consumption. Am J Physiol 1979;H498-505
Suga H, Hayashi T, Shirahata M. Ventricular Systolic Pressure-Volume Area As Predictor Of Cardiac Oxygen Consumption. Am J Physiol 1981;H39-44
Burkhoff D, Mirsky I, Suga H. Assessment Of Systolic And Diastolic Ventricular Properties Via Pressure-Volume Analysis: A Guide For Clinical, Translational, And Basic Researchers. Am J Physiol Heart Circ 2005;289(2):H501-12
Burkhoff D. Mechanical Properties Of The Heart And Its Interaction With The Vascular System. 2011
Weber DM, Raess DH, et al. Principles of Impella Cardiac Support: The New Science of Cardiac Support in the Cath Lab. Cardiac Interventions Today 2009;SUPP:1-20
Meyns B, Stolinski J, Leunens V, et al. Left Ventricular Support By Catheter-Mounted Axial Flow Pump Reduces Infarct Size. J Am Coll Cardiol 2003;41(7):1087-95
Remmelink M, Sjauw KD, Henriques JP, et al. Effects Of Left Ventricular Unloading By Impella Recover LP2.5 On Coronary Hemodynamics. Catheter. Cardiovasc Interv 2007:70(4):532-37
Aqel RA, Hage FG, Iskandrian AE. Improvement Of Myocardial Perfusion With A Percutaneously Inserted Left Ventricular Assist Device. J Nucl Cardiol 2009doi:10.1007/s12350-009-9127-4
Lam K, Sjauw KD, Henriques JP, de Mol BA. Improved Microcirculation In Patients With An Acute ST-Elevation Myocardial Infarction Treated With The Impella LP2.5 Percutaneous Left Ventricular Assist Device. Clin Res Cardiol 2009; DOI 10.1007/s00392-009-0006-4
Reesink KD, Dekker AL, Van Ommen V, et al. Miniature Intra-cardiac Assist Device Provides More Effective Cardiac Unloading And Circulatory Support During Severe Left Heart Failure Than Intra-aortic Balloon Pumping. Chest 2004;126(3):896-902
Valgimigli M, Steendijk P, Sianos G, et al. Left Ventricular Unloading And Concomitant Total Cardiac Output Increase By The Use Of Percutaneous Impella Recover LP 2.5 Assist Device During High-Risk Coronary Intervention. Catheter Cardiovasc Interv 2005;65(2):263-67
Remmelink M. Sjauw KD, Henriques JP, et al. Effects Of Mechanical Left Ventricular Unloading By Impella On Left Ventricular Dynamics In High-Risk And Primary Percutaneous Coronary Intervention Patients. Catheter Cardiovasc Interv 2010;75(2)187-94
Naidu S. Novel Percutaneous Cardiac Assist Devices. The Science of and Indications for Hemodynamic Support. Circulation.2011; 123: 533-543
Sauren LDC, Accord RE, Hamzeh K, et al. Combined Impella And Intra-Aortic Balloon Pump Support To Improve Both Ventricular Unloading And Coronary Blood Flow For Myocardial Recovery: An Experimental Study. Artif Organs 2007;31(11):839-42
Dixon SR, Henriques JP, Mauri L, et al. A Prospective Feasibility Trial Investigating The Use Of The Impella 2.5 System In Patients Undergoing High-Risk Percutaneous Coronary Intervention (The PROTECT I Trial). J Am Coll Cardiol Intv 2009;2:91-96
Engstrom AE, Piek JJ, Henriques JP. Percutaneous Left Ventricular Assist Devices For High-Risk Percutaneous Coronary Intervention. Expert Reviews 2010:1247-55
Sjauw KD, Konorza T, Erbel R, et al. Supported High-Risk Percutaneous Coronary Intervention With The Impella 2.5 Device, The Europella Registry. J Am Coll Cardiol 2009;54(25):2430-34
Kovacic JC, Nguyen H, Karajgikar R, et al. The Impella Recover 2.5 And TandemHeart Ventricular Assist Devices Are Safe And Associated With Equivalent Clinical Outcomes In Patients Undergoing High-Risk Percutaneous Coronary Intervention. Online Manuscript 2011
Burzotta F, Paloscia L, Trani C, et al. Feasibility And Long-Term Safety Of Elective Impella-Assisted High-Risk Percutaneous Coronary Intervention: A Pilot Two-Centre Study. J Cardiovasc Med. 2008 oct;9(10):1004-10
Ferreiro JL, Gomez-Hospital JA, Cequier AR, et al. Use Of Impella Recover LP 2.5 In Elective High Risk Percutaneous Coronary Intervention Int J Cardiol 2009; doi:10.1016/j.ijcard.2009.08.003
Seyfarth M, Sibbing D, Bauer I, et al. A Randomized Clinical Trial To Evaluate The Safety And Efficacy Of A Percutaneous Left Ventricular Assist Device Versus Intra-Aortic Balloon Pumping For Treatment Of Cardiogenic Shock Caused By Myocardial Infarction. J Am Coll Cardiol 2008;52(19):1584-88
Sjauw KD, Remmelink M, Baan J, et al. Preliminary Experience Of The MACH 2 Trial: Safety And Feasibility Of The Left Ventricular Support With The Impella 2.5 Device In Patients With Acute ST-Segment Elevations Myocardial Infarction. J Am Coll Cardiol 2007;914-211:29B
Engström A, Sjauw K, Baan J, et al. Long-term safety and sustained left ventricular recovery: long-term results of percutaneous left ventricular support with Impella LP2.5 in ST-elevation myocardial infarction. EuroIntervention. 2011 Feb;6(7):860-5
Samuels LE, Kaufman MS, Thomas MP, et al. Pharmacological Criteria For Ventricular Assist Device Insertion Following Postcardiotomy Shock: Experience With The Abiomed BVS System. J Card Surg 1999;14:288-93
De Backer D, Biston P, Devriendt J, et al. Comparison Of Dopamine and Norepinephrine In The Treatment Of Shock. N Engl J Med 2010;362(9):779-89
Rogers JG, Butler J, Lansman SL, et al. Chronic Mechanical Circulatory Support For Inotrope-Dependent Heart Failure Patients Who Are Not Transplant Candidates: Results Of The Intrepid Trial. J Am Coll Cardiol 2007;50(8):741-47
Sjauw KD, Engstrom AE, Vis MM, et al. A Systematic Review And Meta-Analysis Of Intra Aortic Balloon Pump Therapy In ST-Elevation Myocardial Infarction: Should We Change The Guidelines? Eur Heart J (2009) 30 (4):459-68
Perera D, Stables R, Thomas M, et al. Elective Intra-aortic Balloon Counterpulsation During High-Risk Percutaneous Coronary Intervention: A Randomized Controlled Trial. JAMA 2010;304(8):867-74
Prondzinski R, Lemm H, Swyter M, et al. Intra-Aortic Balloon Counterpulsation In Patients With Acute Myocardial Infarction Complicated By Cardiogenic Shock: The Prospective, Randomized IABP SHOCK Trial For Attenuation Of Multiorgan Dysfunction Syndrome. Crit Care Med 2010;38(1):152-60
Stone GW, Marsalese D, Brodie Br, et al. A Prospective, Randomized Evaluation Of Prophylactic Intra-Aortic Balloon Counterpulsation In High Risk Patients With Acute Myocardial Infarction Treated With Primary Angioplasty. Second Primary Angioplasty In Myocardial Infarction (PAMI-II) Trial Investigators. J Am Coll Cardiol 1997;29(7):1459-67
Rastan AJ, Tillmann E, Subramanian S, et al. Visceral Arterial Compromise During Intra-Aortic Balloon Counterpulsation Therapy Circulation 2010;122:S92-S99
Other Percutaneous Cardiac Support Devices
Kawashima Dai, Gojo Satoshi, et al. Left Ventricular Mechanical Support with Impella Provides More Ventricular Unloading in Heart Failure than Extracorporeal Membrane Oxygenation. ASAIO Journal 2011
Burkhoff D, Cohen H, Brunckhorst C, O’Neill WW. A Randomized Multicenter Clinical Study To Evaluate The Safety And Efficacy Of The Tandem Heart Percutaneous Ventricular Assist Device Versus Conventional Therapy With Intra Aortic Balloon Pumping For Treatment Of Cardiogenic Shock. Am. Heart J 2006;152(3)469e1-e8
Kar B, Forrester M, Gemmato C, et al. Use Of The TandemHeart Percutaneous Ventricular Assist Device To Support Patients Undergoing High-Risk Percutaneous Coronary Intervention. J Invasive Cardiol 2006;18(3):93-96
Thiele H, Smalling RW, Schuler GC. Percutaneous Left Ventricular Assist Devices In Acute Myocardial Infarction Complicated By Cardiogenic Shock. Eur Heart J 2007;28(17):2057-63
Anderson M, Smedira N, Samuels L, et al. Use Of The AB5000 Ventricular Assist Device In Cardiogenic Shock After Acute Myocardial Infarction. Ann Thorac Surg 2010;90(3):706-712
“It’s making this product available for everybody so that they can increase the complexity of the cases they do. With the Abiomed support team available, it’s changing how everybody is practicing.”