Impella®
Impella®
Disease States
Therapies
Resources

Disease states

Cardiomyopathy

Cardiomyopathy is a spectrum of diseases in which the heart muscle becomes enlarged, thick or rigid, causing it to weaken. Eventually the heart may not be able to pump enough blood to the body, known as cardiogenic shock. It can be difficult to diagnose because it may present with no or little prior symptoms.

Cardiomyopathies can be genetic (present at birth) or acquired. A recent study found that about four in ten cardiomyopathies are genetic.1

Cardiomyopathies often occur in young, otherwise healthy people, and expecting or new moms. They can cause advanced heart failure, heart attacks leading to cardiogenic shock, or even cardiac death.

 

Peripartum Cardiomyopathy (PPCM)

A rare form of the disease that occurs in women during the final months of pregnancy through five months after delivery. It remains a major cause of maternal morbidity and mortality.2,3

Symptoms can be mild to severe, and sometimes mimic pregnancy symptoms, such as swelling of the feet and legs and shortness of breath.

 

Myocarditis

A rare inflammation of the heart muscle, is another form of cardiomyopathy. It can be caused by a viral or bacterial infection, autoimmune disease, reaction to medication, or other causes and it is often difficult to diagnose. It is more common in young adults than in other groups, and often they are otherwise healthy.

 

Impella products used during cardiogenic shock caused by cardiomyopathy:

Impella 2.5® Heart Pump >

Impella CP® Heart Pump >

Impella 5.0®/LD® Heart Pump >

 

 

 

References:

1. https://www.escardio.org/The-ESC/Press-Office/Press-releases/Four-in-ten-cardiomyopathies-a-major-cause-of-sudden-death-in-young-people-a
2. http://www.ajconline.org/article/S0002-9149(16)30562-8/fulltext
3. http://www.onlinejacc.org/content/66/8/905
4. http://www.nejm.org/doi/full/10.1056/NEJM200105243442101
5. https://jamanetwork.com/journals/jama/fullarticle/192436
6. http://circ.ahajournals.org/content/111/16/2050.full
7. http://www.thelancet.com/journals/lancet/ article/PIIS0140-6736(16)31012-1/abstract
8. https://www.myocarditisfoundation.org/about-myocarditis/
9. https://www.myocarditisfoundation.org/about-myocarditis/