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Postcardiotomy Shock Patient Transported While on BVS® Receives Heart Transplant
A 53-year-old male with a history of coronary artery disease, chest pain, arrhythmias and hypertension underwent a routine diagnostic cardiac catheterization which revealed a 50% occlusion of the LAD, 70% occlusion of the secondary diagonal lesion and a 40-50% occlusion of the mid-circumflex. At that time, angioplasty was performed and the patient was discharged to home. Two weeks later, the patient returned to the hospital with recurring chest pain, a stent was placed and the patient was discharged. Two weeks later, the patient again presented to the hospital with chest where a repeat cardiac catheterization revealed a dramatic worsening of his disease. The patient underwent cornoary artery bypass surgery the next day. During the operative course, the patient was unable to be weaned from cardio-pulmonary bypass and an ABIOMED BVS 5000 was implanted. The patient was then transported via mobile ICU to a regional cardiac transplant center. Four days later the decision was made to place the patient on the cardiac transplant list. He was transitioned to a longer term cardiac assist device at that time. Two months later the patient underwent a cardiac transplant, he was discharged to home two weeks later.

History
A 53-year-old male with a history of CAD, unstable angina, VF, HTN and hypercholesterolemia underwent a diagnostic cardiac catheterization which revealed a 50% LAD, 70% secondary diagonal lesion and a 40-50% mid-circumflex lesion and a normal RCA. At that time, angioplasty was performed to the two diagonal lesions and the patient was discharged. Two weeks later, the patient returned to the hospital with angina and a stent was placed to the LAD. Two weeks later, the patient again presented to the hospital with angina where a repeat cardiac catheterization revealed a dramatic worsening of his disease, with a 90% LAD, 70-80% LM, 80% circumflex, 80% diagonal, moderate RCA disease and an EF of 35%. The patient was scheduled for surgery the next day. The patient remained hemodynamically stable with a HR of 86, BP of 136/68, and a SaO2 of 96%.

Operative Summary
A CABG x 4 was performed without complication. However, within 40 minutes of arrival in the ICU, the patient went into refractory ventricular fibrillation, requiring internal cardiac massage. He was taken to the OR and placed emergently on CPB within 45 minutes, wherein his LAD was regrafted. The patient failed to wean from bypass despite maximal inotropic support. The ABIOMED BVS LVAD was implanted with a 32 Fr. atrial cannula into the SPV and a 10 mm Hemashield cannula was anastomosed to the ascending aorta. The patient was successfully weaned from CPB, with an LVAD flow rate of 5.7 L/min and was transferred to the ICU in stable hemodynamic condition.

Post-Operative
On POD 1, the patient was transported via mobile ICU to the regional cardiac transplant center for further evaluation. On POD 4, there was still no evidence of myocardial recovery and the patient was neurologically intact. A decision was made to transfer the patient to a long-term implantable LVAS. Approximately two months later, a suitable donor heart became available, and a successful orthotopic heart transplant was performed without complication. The patient was discharged home two weeks later, and has returned to normal daily activities.

Patient Data
Indication for Use: Post-cardiotomy cardiogenic shock
Type of support: LVAD
Age: 53 Sex: M Weight: 78.2 kg Height: 183 cm BSA: 2.0 m2

Surgical Data
Surgical Procedure: CABG x 4 with subsequent emergent CABG x1 regrafting of LAD
Total CPB time: 5 Hours
Attempts to wean CPB: 1
Time between CPB and LVAD: 45 minutes
IABP prior to LVAD: No
Cannulation: Right SPV - 32 F. atrial. Ascending Aorta - 10 mm. Hemashield

Patient Hemodynamics

Pre Implant On BVS Support
MAP: 66 78
RAP: 14  15
PAP: 40/19 21/14
CI:  1.6  2.4
EF: 10% N/A
L/M: N/A 4.5-5.2



 

 


 

Organ Function on BVS Support
Liver: Normal (SGOT 22, SGPT 28)
Kidney: Creatinine 1.3, BUN 14

Anticoagulation Therapy
Titrated heparin initiation time: 9 hours post BVS implant
Chest tube drainage: 60cc/hr avg.
ACT range: 150-220 seconds